| Data Details | |
| Disease Name | idiopathic pulmonary fibrosis |
| Tissue | cell line |
| Database | GEO |
| Data ID | GSE85268 |
| Data Type | expression |
| Platform | GPL15207 |
| Species | homo sapiens |
| Sample Number | 68 |
| PubMed ID | 28157391 |
| Title | Microbes associate with host innate immune response in idiopathic pulmonary fibrosis |
| Data Description | "Sixty-eight COMET-IPF participants with matched PBMC microarray data and 16s rRNA sequencing data are included in this study. In addition, 32//68 patients have matched leukocyte phenotypes by flow cytometry. Lung fibroblasts derived from transbronchial biopsy of COMET-IPF patients (n=27) were cultured in vitro with growth media. Fibroblasts were treated for 24 hours with or without CpG-ODN. A > 2 fold change in alpha smooth muscle actin expression (i.E. Treated vs. Untreated) was deemed CpG-ODN ""responsive"". Therefore, 27//68 patients have CpG-ODN reponsive data.This series contains the gene expression data for the 68 PBMC samples from COMET-IPF participants." |
| Keyword | pulmonary fibrosis non-coding RNA |
| Download | |
| Data Details | |
| Disease Name | idiopathic pulmonary fibrosis |
| Tissue | blood |
| Database | GEO |
| Data ID | GSE85268 |
| Data Type | expression |
| Platform | GPL15207 |
| Species | homo sapiens |
| Sample Number | 68 |
| PubMed ID | 28157391 |
| Title | Microbes associate with host innate immune response in idiopathic pulmonary fibrosis |
| Data Description | "Sixty-eight COMET-IPF participants with matched PBMC microarray data and 16s rRNA sequencing data are included in this study. In addition, 32/68 patients have matched leukocyte phenotypes by flow cytometry. Lung fibroblasts derived from transbronchial biopsy of COMET-IPF patients (n=27) were cultured in vitro with growth media. Fibroblasts were treated for 24 hours with or without CpG-ODN (hypomethylated DNA; 10 ?M). A > 2 fold change in alpha smooth muscle actin expression (i.e. treated vs. untreated) was deemed CpG-ODN ""responsive"". Therefore, 27/68 patients have CpG-ODN reponsive data." |
| Keyword | pulmonary fibrosis non-coding RNA |
| Download |
FDRdb: Fibrosis Disease-associated RNAnome database
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